Editorials Brittle asthma: fiend or phantom?
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منابع مشابه
Brittle asthma.
Brittle asthma is a rare form of severe asthma characterized by a wide variation of Peak Expiratory Flow (PEF), in spite of heavy doses of steroides. Brittle asthmatic patients had very serious and often, life threatening, attacks. Type 1 brittle asthma is characterized by a mantained PEF variability despite therapy, and it affected mostly female, aged between 15 and 55 years. Type 1 is associa...
متن کاملSubcutaneous terbutaline and control of brittle asthma or appreciable morning dipping.
In a pilot study two patients with brittle asthma and two with morning dipping received terbutaline or a placebo administered subcutaneously either by continuous infusion or in injections every six hours. In two patients brittle asthma was completely suppressed by terbutaline 1 mg/day given by either method. In the two others early morning dipping responded only to continuous subcutaneous infus...
متن کاملDietary antioxidants and magnesium in type 1 brittle asthma: a case control study.
BACKGROUND Type 1 brittle asthma is a rare form of asthma. Atopy, psychosocial factors and diet may contribute to this condition. As increased dietary magnesium has a beneficial effect on lung function and selenium, vitamins A, C and E have antioxidant properties, a study was undertaken to test the hypothesis that patients with brittle asthma have diets deficient in these nutrients compared wit...
متن کاملOmalizumab treatment in brittle asthma
Asthma is a heterogeneous disease with variable characteristics such as lung function, symptoms and control, body weight, pattern of inflammation, and response to treatment. Brittle asthma is one of clinical phenotypes of asthma with unclear pathogenic mechanisms and appropriate treatment. Analysis of 2 described cases suggests that omalizumab could be useful in the treatment of brittle allergi...
متن کاملContinuous intravenous therapy with theophylline in patients with brittle bronchial asthma.
I read with interest the case report (Spielberg and van Denbrink, Eur Respir J., 1, 471-472) from Davos on a patient with brittle asthma treated with a continuous infusion of theophylline. I was surprised to see that our paper on the treatment of brittle asthma with continuous subcutaneous infusions of terbutaline was not referred to [1]. Since that preliminary study which showed excellent cont...
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